It is the first Covid-19-related postponement of the season.
No make-up date for the game — which was to be the finale of a three-game series between the two teams at Guaranteed Rate Field in Chicago — has been announced.
The Guardians’ next scheduled contest is Friday against the Minnesota Twins in Minneapolis.
A spokesperson for the Guardians said the club needed a few hours to arrange logistics and travel coordination before issuing a team statement.
This is a developing story and will be updated.